Lead Sponsor

Indiana Hand to Shoulder Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Adults (18 years of age or older)
•Patients presenting with symptomatic 1st CMC arthritis with or without scaphotrapeziotrapezoid arthritis
•Eaton Classification stage II, III, or IV OA of the first CMC joint based on xrays
•Patients who plan to undergo a ligament reconstruction and tendon interposition (LRTI) or thumb suspensionplasty procedure within 6 months of enrolling to study
•Bilateral thumbs included

•\<18 years age
•Prior surgical history of ipsilateral 1st CMC arthroplasty or procedures involving thumb CMC joints
•Prior ipsilateral tendon rupture or ipsilateral peripheral nerve palsy
•History of opioid dependency or current chronic opioid use
•Contraindication to acetaminophen use
•Contraindication to NSAID use
•Contraindication or known allergy to peripheral nerve blockade, including coagulopathy
•Contraindication to supraclavicular block due to anatomic variability or inability to tolerate phrenic nerve blockade.
•Contraindication to multivitamin use
•Liver dysfunction

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