Asthmatic patients classified by severity Mild (achieved control with using low-dose ICS or as-needed ICS-formoterol) or Moderate (achieved controlled with using low-dose ICS/LABA or Severe ((achieved controlled with using medium to high dose ICS/LABA)
Post-bronchodilator (Salbutamol) FEV1/FVC ratio less than 0.75 or below the Lower Limit of Normal (LLN) and Post-bronchodilator (Salbutamol) FEV1 predicted \< 80% with or without bronchodilator response
History of smoking less than 10 pack-years or current smoking
Patients who able to do spirometry without contraindication
asthma control was defined by ACQ6 \< 1.5
You may not be if
Contraindication for spirometry
Chest x-ray suggested any chronic lung diseased
Contraindication for anticholinergic drug
History of asthma exacerbation within 12 weeks before visit 1
History of taking LAMA within 6 months before visit 1
Clareo Health | Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study)