Age ≥70 years.

Clinical Frailty Scale ≥4 and ≤7.

Diagnosis of:

* Untreated systolic hypertension, i.e. unattended office SBP ≥150 mmHg without AHT, or;

* Uncontrolled systolic hypertension, i.e. unattended office SBP ≥150 mmHg despite AHT.

Will be starting (untreated) or adding (uncontrolled) AHT in the near future for (further) reducing SBP by ≥10 mmHg while reaching a treatment target of unattended office SBP

≤140 mmHg, while keeping unattended office diastolic blood pressure ≥70 mmHg, with the indication of primary or secondary prevention of vascular events, judged by the treating physician (geriatrician or primary care physician)

Able to understand and perform study related procedures.

The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly

What this study is about