Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hull University Teaching Hospitals NHS Trust
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females aged ≥18 years.
Have a diagnosis of chronic respiratory disease (COPD, asthma, interstitial lung disease, chronic cough, cystic fibrosis, and/or bronchiectasis) confirmed by a respiratory consultant.
Exhibit symptoms consistent with airway reflux, demonstrated by a score ≥14 on the Hull Airways Reflux Questionnaire
Are being initiated on azithromycin as part of routine clinical care, as judged by their usual respiratory clinician. This will include all common treatment regimes, 250mg once daily, 250mg three times per week, and 500mg three time per week.
Are willing and able to consent to all study procedures.
You may not be if
Previous treatment with long-term macrolides in the past 3 months.
Unable to be investigated with HROM due to contraindications such as anatomical abnormalities or diseases of the oesophagus or unwilling/ unable to be investigated with HROM based on the clinical judgement of the investigators due to severity of lung disease.
Have another cardiorespiratory cause for their symptoms (such as heart failure or lung cancer).
Women of child bearing potential not using effective means of contraception.
Are unable or unwilling to consent to or complete the study procedures.
Clareo Health | Azithromycin and Oesophageal Function in Respiratory Disease
