BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY

Exclusion Criteria

• •Significant intravesical median lobe hyperplasia.
• •Suspicious lesion on mpMRI prostate
• •History of prostate, bladder or urethral surgery.
• •History of prostate cancer
• •Presence of stones, bladder diverticulum and/or bladder tumor
• •History of long-term indwelling catheter.
• •Urethral stricture
• •Known coagulopathy or on anticoagulant
• •Presence of a pacemaker.
• •Active infection
• •Dysuria due to bladder dysfunction.
• •Serious medical illness, including any of the following: uncontrolled congestive heart failure, uncontrolled angina, myocardial infarction, cerebrovascular event within 6 months prior to the screening visit.
• •Neurological disorders that would impact bladder function (e.g., multiple sclerosis, Parkinson's disease, spinal cord injury).
• •Contraindications for mpMRI exam or MR contrast
• •Acute and/or chronic renal failure (GFR \<50 ml/min and serum creatinine \> 1.5 mg/d).
• •Patient currently participating in another interventional clinical trial.