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Point-of-care echocardiography (POC-Echo) is used to determine left ventricular systolic and diastolic dysfunction (LVDD), inferior vena cava (IVC) dynamics and volume status in cirrhosis and Acute-on-chronic liver failure ACLF accurately. We will assess IVC dynamics, LV systolic function \[LV ejection fraction (EF) \& cardiac output (CO)\], and diastolic dysfunction (E/e', e' and E/A ratio) and urinary biomarkers (cystatin C and NGAL) in patients with cirrhosis and ACLF with hepatorenal syndrome-acute kidney injury (HRS-AKI).
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
PGIMER
Chandigarh, National Capital Territory of Delhi, India
Start Date
December 15, 2021
Primary Completion Date
March 15, 2023
Completion Date
June 15, 2023
Last Updated
May 1, 2023
75
ESTIMATED participants
Echocardiographic assessment
DIAGNOSTIC_TEST
Lead Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
NCT07343037
NCT07275554
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