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Potassium Supplementation to Reduce Blood Pressure | Clinical Trials | Clareo Health

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Potassium Supplementation to Reduce Blood Pressure

Testing the Potential Effect of a Potassium-rich Water Intervention on Blood Pressure in Mild to Moderately Hypertensive Adults: a Double-blind Randomised Controlled Trial

NCT05412654•Oxford Brookes University

View on ClinicalTrials.gov

Summary

The aim of this study is to conduct a definitive trial to assess the efficacy of consuming 1L/day of water rich in potassium to reduce blood pressure in mild to moderately hypertensive adults. The objective is to assess the potential effect of the intervention on reducing systolic blood pressure. This study will comprise of a 4 week, double-blind, parallel randomised controlled trial. Participants will be adults with systolic blood pressure measurements of 130mmHg or greater. The intervention comprises advice to consume bottled water rich in potassium. The comparator will be regular bottled mineral water.This study will recruit 40 people with elevated systolic blood pressure (≥130mmHg) who are not regularly taking antihypertensive medication.

Eligibility

Age

20 - 64 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Willing and able to provide informed consent
•Between 20 to 64 years old
•English speaking
•Adults who are not receiving antihypertensive pharmacological treatment
•Recent (within 6 months) and latest systolic blood pressure measurement ≥130mmHg and/or diastolic ≥85 mmHg
•Have access to internet and equipment for video calling
•Able to post samples and equipment to OxBCNH
•Physically able to take own body measurements and blood pressure

Exclusion Criteria

•Participation in another research study
•Unable to read and understand the instructions provided in English
•Unable to comply with experimental procedures or not follow testing safety guidelines
•People with cardiovascular conditions: heart attack or stroke within the last 3 months, heart failure of grade II New York Heart Association and more severe, or prolonged QT syndrome, angina, arrhythmia or atrial fibrillation.
•Uncontrolled type 2 diabetes (HbA1c\> 9%)
•Type 2 diabetes controlled using exogenous insulin
•Previous or current diagnosis of diabetes complications such as nephropathy, retinopathy and neuropathy.
•People with type 1 diabetes
•Currently on any medication that may lead to hyperkalemia or fluid retention
•Currently being assessed for diagnosis of hypertension (not receiving treatment for high blood pressure)
+6 more criteria

Locations (1)

Oxford Brookes University

Oxford, Oxfordshire, United Kingdom

Key Dates

Start Date

July 30, 2022

Primary Completion Date

December 1, 2023

Completion Date

December 1, 2023

Last Updated

April 4, 2024

Enrollment

ACTUAL participants

Conditions

Prehypertension

Interventions

High potassium water

DIETARY_SUPPLEMENT

Control low potassium water

DIETARY_SUPPLEMENT

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 4, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Potassium Supplementation to Reduce Blood Pressure

Inclusion Criteria

Exclusion Criteria

Evaluation of Physical Fitness and Hemodynamics Across a Diverse Population

Pranayama and Jacobson's Progressive Muscle Relaxation Technique in Pre-hypertensive Patients

Project WHADE: A Partner-Based Physical Activity Program for Women

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