Fasting-mimicking Diet in Treatment of Depressive Symptoms in IBD

Exclusion Criteria

• •Subjects who are reliant on partial or total parenteral nutrition
• •Subjects with prior gastrointestinal surgery and consequences such as short bowel syndrome, ostomy of small or large intestine, total colectomy, proctocolectomy, or ileoanal pouch
• •Subjects with diabetes or celiac disease
• •Subjects with a body mass index (BMI) lower than 18
• •Subjects suffering from malnutrition or at high risk of malnutrition assessed by a score of ≥6 on the abridged patient generated subjective global assessment (PGSGA)
• •Subjects allergic to nuts
• •Subjects currently on a fasting/intermittent type caloric restricted diet
• •History of psychotic or bipolar disorders or experiencing suicidal thoughts
• •Pregnant women, women who are breast feeding, or women planning on becoming pregnant
• •Subjects with immune-compromised condition other than inflammatory bowel disease (e.g. AIDS, lymphoma)
• •Subjects with severe uncontrolled cardiovascular or respiratory disease or active malignancy
• •Unable to read English or provide informed consent