Study of the Efficacy and Safety of AMT-101 in Combination With Adalimumab in Subjects With Ulcerative Colitis (MARKET)

Exclusion Criteria

• •Known gastrologic, or systemic condition that may compromise severity or diagnosis of disease.
• •History or current evidence of colonic or abdominal abnormalities.
• •Prohibited therapies or procedures before the screening period as specified per protocol.
• •A concurrent clinically significant, serious, unstable, or uncontrolled underlying cardiovascular, pulmonary, hepatic, renal, gastrointestinal, genitourinary, hematological, coagulation, immunological, endocrine/metabolic, or other medical disorder that, in the opinion of the investigator, might confound the study results, pose additional risk to the subject, or interfere with the subject's ability to participate fully in the study.
• •Pregnant or lactating females.
• •Current or recent history of alcohol dependence, illicit drug use, mental or legal incapacitation, or a history of clinically significant psychiatric disorders that, in the opinion of the investigator, may interfere with the subject's ability to comply with the study procedures.
• •Unable to attend study visits or comply with procedures.
• •Previous exposure to AMT-101 or similar and known hypersensitivity to AMT-101 or its excipients.