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PREventing Pain After Surgery | Clinical Trials | Clareo Health

RECRUITINGNA

PREventing Pain After Surgery

PREventing Pain After Surgery: a Feasibility and Acceptability Study of Acceptance and Commitment Therapy for the Prevention of Chronic Post-surgical Pain (PREPS)

NCT05306665•Brigham and Women's Hospital

View on ClinicalTrials.gov

Summary

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

Eligibility

Age

22 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foraminotomy
•age 22 and older
•able to communicate fluently in English

Exclusion Criteria

•inability to complete study procedures due to delirium, dementia, psychosis, or other cognitive impairment
•have a history of severe neurologic movement disorder
•are pregnant or intent to become pregnant during study
•have undergone previous spinal surgery
•have spinal deformity, pseudarthrosis, trauma, infection, or tumor as primary indication for surgery
•have undergone Acceptance and Commitment Therapy in last 2 years

Locations (1)

Brigham and Women's Hospital

Chestnut Hill, Massachusetts, United States

Key Dates

Start Date

January 13, 2023

Primary Completion Date

August 1, 2026

Completion Date

August 1, 2026

Last Updated

October 28, 2024

Enrollment

140

ESTIMATED participants

Conditions

Pain, BackSpinal StenosisDisc HerniationSpondylosisSpondylolisthesisBack Injuries

Interventions

ACT intervention

BEHAVIORAL

Contacts

Samantha M Meints, PhD

CONTACT

6177329014 smeints@bwh.harvard.edu

Marise Cornelius, MBA

CONTACT

mcornelius@bwh.harvard.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 28, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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PREventing Pain After Surgery

Inclusion Criteria

Exclusion Criteria

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