Lead Sponsor

Cairo University

Age

22 - 45 years

Sex

ALL

Healthy Volunteers

Yes

•Patient's age ranges between 22 to 45 years with no sex predilection.
•Medically free patients.
•Maxillary permanent premolar teeth:
•* Diagnosed clinically with pulp necrosis.
•* Absence of pain.
•* Radiographic evidence of two roots or single root with double canals.
•* Slight widening in the periodontal membrane space or with peri-apical radiolucency
•* No response to cold pulp tester and ethyl chloride spray.
•Patients who can understand Modified Visual Analogue Scale (VAS).
•Patients' acceptance to participate in the trial.

•Medically compromised patients.
•Pregnant women.
•If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively.
•Patients reporting bruxism or clenching.
•Teeth with:
•i. Vital teeth. ii. Single canal maxillary premolar teeth iii. Association with swelling or fistulous tract. iv. Acute peri-apical abscess and swelling. v. Mobility Grade II or III. vi. Pocket depth more than 5mm. vii. Previous root canal therapy. viii. Non-restorable teeth: Hopeless tooth
•Immature teeth.
•Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification, root caries.

Related studies

NCT06466941 · Acute Pain, Chronic Post Operative Pain, and more

NCT07556536 · Post Operative Pain, Open Nephrectomy

NCT07482709 · Post Operative Pain in Total Abdominal Hystrectomy

NCT05110989 · Post Operative Pain

NCT07041736 · Post Operative Pain

Evaluation of Postoperative Pain and Bacterial Load Reduction With ProTaper Ultimate Versus ProTaper Gold Rotary Systems