Personalized Ultrasonic Brain Stimulation for Depression

Exclusion Criteria

• •1. History of serious brain injury or other neurologic disorder
• •2. Poorly managed general medical condition
• •3. Pregnant or breast feeding
• •4. Implanted device in the head or neck
• •5. MRI intolerance or contraindication
• •6. Brain stimulation (e.g., ECT, TMS, VNS) in the past month
• •7. Suicidal ideation (Columbia Suicide Severity Rating Scale screen item #2, past month)
• •8. Lifetime history of a serious suicide attempt
• •9. Moderate-to-severe substance use disorder (past 3 months)
• •10. Obsessive compulsive disorder (past month)
• •11. Posttraumatic stress disorder (past month)
• •12. Schizophrenia-spectrum disorder (lifetime)
• •13. Neurocognitive disorder (past year)
• •14. Personality disorder as a current focus of treatment
• •15. Clinically inappropriate for participation in the study as determined by the study team