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If Adrenal Incidentalomas Have the Influences to Occur and Progress in Patients With Stroke
Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke. Stroke is a diseases which could cause of disability and death worldwide. In clinical practice, detailed information about the association between stroke and AIs is not available. In this study, the investigators aimed to investigate the risk for disability and death in the large group of stroke patients with AIs.
Background: Adrenal incidentalomas (AIs) are commonly encountered in transsection imaging which purpose not for suspected adrenal disease. However, part of AIs in patients is associated with Stroke . The investigators aimed to investigate the risk for disability and death in the large group of stroke patients with AIs. Objective: To measure the association between stroke and levels of autonomous cortisol secretion in patients with AIs. Design: Part 1, Retrospective cohort study. From April 1, 2021, to September 30, 2021, cohort patients with stroke were recruited in this study. The investigators assess the standardised incidence rate of AIs in all patients. Meanwhile, detail information about stroke disease、patient and AIs characteristics were record. Part 2, Prospective cohort study. From Mar 1, 2022, to Feb 29, 2024, cohort patients with stroke plane to recruit in this study. All patient receive the plasma cortisol level after a 1-mg dexamethasone suppression test. The investigators assess the standardised incidence rate of AIs in all patients. Meanwhile, detail information about stroke disease、patient and AIs characteristics would be record.
Age
18 - 100 years
Sex
ALL
Healthy Volunteers
No
Hao Yan
Beijing, China
Start Date
April 1, 2021
Primary Completion Date
April 1, 2022
Completion Date
February 28, 2029
Last Updated
February 14, 2022
2
ESTIMATED participants
Lead Sponsor
Xuanwu Hospital, Beijing
NCT05093673
NCT06258538
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07371455