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Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment | Clinical Trials | Clareo Health

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Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment

NCT05231824•Drexel University

Summary

Project ReLearn is testing the efficacy and cost-effectiveness of an Artificial Intelligence system for optimizing weight loss coaching. Participants are randomized to a 1-year weekly gold standard behavioral weight loss remote (video) group treatment or the AI-optimized treatment, which is made up of a combination of remote group treatment, short video call and automated message. In the AI-optimized condition, the system monitors outcomes (via wireless scale, mobile phone app, and wristworn tracker) and, each week, assigns each participant the treatments they have responding to the best, within certain time constraints.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Individuals must be of overweight or obese BMI (27-50 kg/m)
•Individuals must be adults (aged 18-70)
•Able and willing to engage in the remote program
•Able to engage in physical activity (defined as walking two city blocks without stopping)
•Individuals must also provide consent for the research team to contact their personal physician if necessary, to provide clearance or to consult about rapid weight loss
•Access and willingness to use an Apple or Android smartphone
•Satisfactory completion of all enrollment procedures

Exclusion Criteria

•Medical condition (e.g., cancer, type I diabetes, psychosis, full-threshold eating disorder) that may pose a risk to the participant during intervention or cause a change in weight
•Currently pregnant, breastfeeding, or planning to become pregnant in the next 12 months
•Recently began or changed the dosage of medication that can cause significant change in weight
•History of bariatric surgery
•Weight loss of \> 5% in the previous 3 months

Locations (1)

Drexel University Center for Weight, Eating and Lifestyle Science

Philadelphia, Pennsylvania, United States

Key Dates

Start Date

March 22, 2022

Primary Completion Date

August 31, 2025

Completion Date

March 31, 2026

Last Updated

August 24, 2025

Enrollment

336

ESTIMATED participants

Conditions

ObesityWeight Loss

Interventions

Standard Behavioral Weight Loss Treatment

BEHAVIORAL

AI-optimized Behavioral Weight Loss Treatment

BEHAVIORAL

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RECRUITING

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 24, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Using Artificial Intelligence to Optimize Delivery of Weight Loss Treatment

Inclusion Criteria

Exclusion Criteria

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