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COMPLETEDNANCT05195021

The Effect of Different Irrigation and Disinfection Methods on Post-operative Pain (PP)

Aim: The aim of this study was to examine post-operative pain (PP) severity after conventional irrigation and sonic activation methods, with and without laser disinfection in mandibular molar teeth di...

Lead sponsor: Biruni University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Biruni University

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Healthy adult patients aged between 18 and 65 years
•2. Moderate to severe pain (4-10) according to a visual analogue scale (VAS)
•3. Mandibular molar teeth diagnosed with symptomatic apical periodontitis (a painful response during mastication and/or percussion or palpation)

Exclusion Criteria

•1. Pregnancy or lactation
•2. Taking analgesics or anti-inflammatory drugs 12 hours before the treatment
•3. Taking antibiotics in the month prior to the treatment
•4. Teeth with calcified root canals, greater than grade I mobility and a 4 mm pocket depth, non-restorable damage, occlusal trauma and previous root canal treatment or an open apex
•5. Allergy to articaine or non-steroid anti-inflammatory drugs

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 18, 2022Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment80

Start dateDec 2020

Last updatedJan 18, 2022

Condition

Post-operative Pain Apical Periodontitis

Locations shown

Biruni University

Istanbul

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 18, 2022Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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