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Comparing the Analgesic Effect of Intraperitoneal and Intravenous Magnesium Sulphate in Diagnostic Gynecological Laparoscopy
Postoperative pain after laparoscopy may be localized pain resulting from incision due to many (two or three) punctures (somatic pain) or due to manipulation of the intra-abdominal organs as ovaries, uterus, omentum, and intestine (visceral pain) or shoulder and back pain caused by retained CO2 in the peritoneal cavity with its irritation effect on the diaphragm.Patients will be divided into two groups: Intraperitoneal (IP) group (20 patients):They will receive 100 ml normal saline infused over 10 min immediately before the induction of anesthesia and then continuous infusion of 500 ml normal saline intraoperatively then intraperitoneal wash of 100 ml normal saline containing 30 mg/kg MgSO4 at the end of laparoscopy. Intravenous (IV) group (20 patients):They will receive 100 ml normal saline containing MgSO4 30 mg/kg infused over 10 min immediately before the induction of anesthesia and then continuous infusion of 500 ml normal saline containing MgSO4 (8mg/kg) intraoperatively then intraperitoneal wash using 100 ml normal saline at the end of laparoscopy
Age
20 - 44 years
Sex
FEMALE
Healthy Volunteers
No
Fouad Soliman
Sohag, Egypt
Start Date
September 2, 2021
Primary Completion Date
February 2, 2022
Completion Date
February 5, 2022
Last Updated
January 26, 2022
44
ESTIMATED participants
intraperitoneal Magnesium sulfate
DRUG
intravenous magnesium sulfate
DRUG
Lead Sponsor
Sohag University
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07046325