Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Exclusion Criteria

• •Mild and Moderate HI (Panels A and B):
• •Has a history of any illness that, in the opinion of the investigator, might confound the results of the study or poses an additional risk to the participant by their participation in the study
• •Is not in sufficient health
• •Is institutionalized/mentally or legally incapacitated
• •Is positive for human immunodeficiency virus (HIV)-1 or HIV-2
• •Has received antiviral and/or immune modulating therapy for hepatitis B virus (HBV) or hepatitis C virus (HCV) within 90 days prior to study start
• •Is taking medication for a chronic condition and has not been on a stable regimen for ≥ 1 month
• •Healthy Controls (Panel C):
• •Has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
• •Is mentally or legally incapacitated
• •Is positive for hepatitis B virus surface antigen (HBsAg), hepatitis C antibodies, HIV-1, or HIV-2
• •Is unable to refrain from or anticipates the use of any medication, including prescription and nonprescription drugs or herbal remedies beginning approximately 2 weeks (or 5 half-lives) prior to first dose of study drug
• •All Participants (Panel A to C):
• •Has a history of cancer (malignancy)
• •Has a history of significant multiple and/or severe allergies
• •Has known hypersensitivity to the active substance or any of the excipients of the study drug
• •Has participated in another investigational study within 4 weeks (or 5 half-lives, whichever is greater) prior to Screening