Evaluation of the Efficacy and Safety of a Hyaluronic Acid Gel in Adhesion Prevention After Open Thyroidectomy.

Exclusion Criteria

• •Pregnant or lactating female patients.
• •Presence of severe and uncontrolled illness such as stroke, hypertension, diabetes, chronic renal failure, coagulopathy, drug abuse.
• •Patients with previous neck radiotherapy within 1 year.
• •Concurrent diseases/conditions which will be unable to evaluate the outcomes.
• •Patients receiving any adhesion prevention adjuvant.
• •Previous history of Keloid or hypertrophic scar.
• •Anticoagulant used within a week from surgery.
• •Subjects are hypersensitive to sodium hyaluronate.
• •Participate in another clinical trial within 1 month.
• •Patients presence of surgical site infection.
• •Patients are with abnormal clinical test (appendix 1) result within one month or ECOG performance status (appendix 2) score ranged from 3-4.