Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test

Exclusion Criteria

• •active illicit drug use,
• •history of a medication reaction requiring emergency medical care,
• •difficulty with blood draws.
• •history of chronic disease, except well controlled thyroid disease,
• •recent use of prescription medications which interfere with metabolism or reproduction (recent = within 5 half-lives of the drug). Use of levothyroxine or seasonal allergy medications is acceptable,
• •history of diabetes in a first degree relative,
• •use of contraceptive pills, patches or vaginal rings within last 4 weeks.
• •hyperlipidemia by fasting lipid panel
• •positive serum pregnancy test (for all women)