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Lead
National Cancer Institute, Egypt
Nitroglycerine is a direct vessel wall vasodilator with more venodilator effect than arterial dilator effect. It is used as an anti-anginal and antihypertensive drug. On the other hand, dexmedetomidine is a highly selective alpha 2 adrenergic agonist with sympatholytic effect. This study aim to compare the efficacy of intraoperative dexmedetomidine infusion versus Nitroglycerin infusion in cancer patients with accidental uncontrolled intraoperative elevation of blood pressure.
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Cancer patients with controlled hypertension and undergoing surgical procedures under general anesthesia
≥ Age 18 years.
You may not be if
patient refusal
patients on Beta blockers
kidney or liver function impairment
bradycardia, any degree of heart block and severe cardiorespiratory disease
Clareo Health | Nitroglycerine Versus Dexmedetomidine Infusion in Intraoperative Management of Uncontrolled Hypertension
