Treatment Outcomes For Functional Dyspepsia Based On Current International Guidelines In Multi-Ethnic Asian Patients

Exclusion Criteria

• •1. Patients with known hypersensitivity to Itopride and/or proton pump inhibitors or to any of the excipients of the study medication
• •2. Patients with a contraindication to any of the study drugs
• •3. Pregnant / breast feeding women
• •4. Presence of family history of GI malignancy or alarm features suggested malignancy - e.g. Unintentional weight loss (≥ 10% of body weight in recent 6 months), GI bleeding
• •5. Patients consuming regular Aspirin or NSAIDs (except low-dose Aspirin at a dose of 325 mg/day or less for cardiovascular prophylaxis)
• •6. History of erosive esophagitis, peptic ulcer disease within 1 year prior to the screening
• •7. History of gastrointestinal (GI) malignancy, primary esophageal motility disorder, documented upper GI surgery
• •8. Patients with any hepatobiliary or pancreatic diseases
• •9. Patients with severe depression, anxiety, or other psychological disorder
• •10. Patients with any terminal disease
• •11. Presence of irritable bowel syndrome (Rome IV criteria) or inflammatory bowel disease (IBD)
• •12. Other conditions determined by the investigator to be inappropriate for this clinical study