Faecal Microbiota Transplantation in Irritable Bowel Syndrome

Exclusion Criteria

• •The use of antibiotics within one month prior to faecal microbiota transplantation
• •The use of probiotics within one month prior to faecal microbiota transplantation
• •History of inflammatory bowel disease or gastrointestinal malignancy, systemic autoimmune diseases (ongoing or in history)
• •Previous abdominal surgery (other than appendectomy or cholecystectomy or hernioplasty or cesarean section)
• •HIV infection or other active infection
• •Renal or hepatic disease (both defined by biochemistry workup)
• •Diabetes mellitus, abnormal thyroid functions not controlled by thyroid medications
• •Bipolar disorder or schizophrenia (ongoing or history thereof), moderately severe depression defined by Patient Health Questionnaire-9 (PHQ-9) score \> 15
• •Anxiety defined by a Generalised Anxiety Disorder 7 (GAD7) score \> 10
• •Current pregnancy and lactation