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Phenotype, Genotype and Biomarkers 2 | Clinical Trials | Clareo Health

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Active Not RecruitingNCT04875416

Phenotype, Genotype and Biomarkers 2

The purpose of this study is to learn more about amyotrophic lateral sclerosis (ALS) and other related neurodegenerative diseases, including frontotemporal dementia (FTD), primary lateral sclerosis (P...

Lead sponsor: University of Miami•3 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Miami

Collaborators

National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)

Age

7 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Clinical diagnosis or suspicion of ALS or a related disorder, including, but not limited to, ALS-FTD, PLS, HSP, FTD, Multisystem Proteinopathy (MSP) and PMA.
•Subject is able and willing to comply with study procedures
•Family member of an enrolled affected primary participant

Exclusion Criteria

•Subjects with a condition or who are in a situation which, in the PI's opinion, could confound the study finding or may interfere significantly with the individual's participation and compliance with the study protocol -- including but not limited to neurological, psychological and/or medical conditions
•Subjects with a condition or who are in a situation which, in the PI's opinion, could confound the study finding or may interfere significantly with the individual's participation and compliance with the study protocol -- including but not limited to neurological, psychological and/or medical conditions

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 23, 2026Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

Phase—

Enrollment217

Start dateJan 2021

Last updatedMar 23, 2026

Condition

Amyotrophic Lateral Sclerosis Hereditary Spastic Paraplegia Primary Lateral Sclerosis Progressive Muscular Atrophy Frontotemporal Dementia

Locations shown

University of Miami

Miami, Florida

University of Kansas Medical Center

Kansas City, Kansas

University of Pennsylvania

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 23, 2026Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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