Long-term Elobixibat for Chronic Constipation

Exclusion Criteria

• •Patients with organic constipation or patients with suspected organic constipation.
• •Patients with or suspected of having functional ileus.
• •Patients with or suspected of having an inguinal hernia.
• •Patients with a history of open surgery within 12 weeks before obtaining consent (excluding appendicitis resection).
• •Patients with a history of surgical or endoscopic procedures related to cholecystectomy and papillotomy.
• •Patients with complications of malignancy.
• •Pregnant women, lactating women, women who may be currently pregnant, or patients who cannot consent to use contraception while participating in the study.
• •Patients with serious renal, liver, or cardiac disease.
• •Patients who are allergic to this study drug.
• •Patients who have previously taken Goufis tablets (elobixibat).
• •Patients with contraindications to rescue drugs (bisacodyl suppositories and prusenide tablets).
• •Patients who are participating in another clinical study or who were participating in another clinical study within 4 weeks before consent was obtained, excluding observational studies.
• •Patients who are judged by the principal investigator or sub-physician to be inappropriate for conducting this research.