Tracking Response to Antidepressants in Advance of Investigational Trials

Exclusion Criteria

• •Participant is pregnant, breast-feeding, or planning to become pregnant.
• •A history or presence of a clinically significant hepatic, renal, gastrointestinal, cardiovascular, endocrine, respiratory, immunologic, hematologic, dermatologic, or neurologic abnormality, which in the opinion of the investigator may impact participant safety or study results.
• •Participant has a history of any psychiatric condition other than MDD, which in the opinion of the investigator is primary, or any other psychiatric or neurologic disorder or symptom that could pose undue risk to the participant or compromise the study.
• •Any participant who represents an acute suicidal risk in the opinion of the investigator.
• •Moderate or severe substance use disorder within 90 days prior to screen, according to DSM-5 criteria that in the opinion of the investigator could pose undue risk to the participant, or compromise the study.
• •Any condition that, in the opinion of the investigator, makes the participant unsuitable for the study.