Microwave Ablation Combined With Chemotherapy in the Treatment of Pancreatic Cancer Oligohepatic Metastasis

Inclusion Criteria

• •Age: 18 to 75years old, male or female;
• •ECOG PS: 0-2 points;
• •Patients with pancreatic ductal adenocarcinoma diagnosed by histology or cytology;
• •Expected survival time\> 3 months;
• •The functions of important organs meet the following requirements;
• •The maximum diameter of single lesion ≤ 5cm or the number of multiple lesions ≤ 5 and the maximum diameter ≤ 3cm;
• •Measurable lesions that meet RECIST criteria.
• •1. Platelet ≥75×109/L, hemoglobin ≥85g/L，white blood cell ≥ 3.0 × 109 / L;
• •2. Total bilirubin ≤ 1.5 times upper limit of normal value (ULN) ; ALT and AST ≤ 5 times ULN ;
• •3. Albumin ≥ 28g / L;
• •4. Creatinine ≤ 1.5 times ULN, or creatinine clearance rate ≥ 50ml / min;
• •Women of childbearing age must undergo a negative pregnancy test (βHCG) before starting treatment. Women and men of childbearing age (sexual relationships with women of childbearing age) must agree to use them effectively during treatment and 3 months after the last dose of treatment Contraceptive measures;
• •Signature of patient information and informed consent.
• •Patients who did not participate in other clinical trials within 4 weeks before screening; those who failed in other trials but met the requirements of this trial could be enrolled.