Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women

Exclusion Criteria

• •1. Inability to receive adenosine or regadenoson (for example, severe reactive airway disease, marked hypotension, or advanced atrioventricular block without pacemaker.
• •2. Severe cardiomyopathy (ejection fraction \<30%)
• •3. Extremely tortuous or calcified coronary arteries precluding FFR/iFR measurements
• •4. Patients with left main coronary artery disease requiring revascularization
• •5. Female of child baring age should have negative pregnancy test
• •6. Subject is pregnant or breast feeding, or planning to become pregnant
• •7. Contraindication to non-invasive stress imaging including severe claustrophobia, renal disease with GFR \<30 where CMR is indication, any metal in the body which is a contraindication to CMR, allergy to gadolinium contrast
• •8. ICD or PPM