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It has been shown that adipokines (resistin, leptin, adiponectin) secreted from adipose tissue and proinflammatory cytokines such as IL-6, TNF-a are associated with the risk of developing colorectal cancer. However, the role of these factors in predicting clinical response to neoadjuvant therapy in rectal cancers is unknown. In this study, the role of serum adipokine levels before neoadjuvant therapy in predicting clinical response in patients with rectal cancer is investigated. For this purpose, blood will be drawn from patients with rectal cancer who will receive neoadjuvant therapy, serum adipokines will be studied and clinical response to neoadjuvant therapy will be compared.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Istanbul Training and Research Hospital
Istanbul, Turkey (Türkiye)
Start Date
September 1, 2020
Primary Completion Date
December 30, 2022
Completion Date
December 31, 2022
Last Updated
August 8, 2022
60
ESTIMATED participants
serum adipokines
DIAGNOSTIC_TEST
Lead Sponsor
Istanbul Training and Research Hospital
NCT07328087
NCT07018869
Data Source & Attribution
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