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A Novel Score to Predict Risk of Symptomatic Intracerebral Hemorrhage After Stroke Thrombectomy: Derivation, Validation and Comparison With Other Scores
This study sought to develop and validate a new risk stratification score (Henan predicting the risk of intracerebral hemorrhage score, Henan-PRIHS) based on intra-arterial contrast enhanced Flat Detector CT (IA-CEFDCT) to predict symptomatic intra-cerebral hemorrhage (sICH) after stroke thrombectomy.
The Henan-PRIHS was developed from 95 patients who underwent IA-CEFDCT and MT for acute anterior stroke. Patients were classified as having one of three grades according to the presence of contrast filling within the occluded vascular territory. Grade 0 was normal or less contrast filling in affected hemisphere, grade 1 and 2 were small and medium-large area without contrast filling, respectively. The Youden index was used to determine the optimum no contrast filling area cutoff for defining grade 1 and 2. The score was subsequently validated in a different population of 208 patients and compared with three established scores.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Shanghai 6th People's Hospital
Shanghai, China
Start Date
June 1, 2015
Primary Completion Date
December 31, 2019
Completion Date
March 30, 2020
Last Updated
November 24, 2023
300
ACTUAL participants
intra-arterial contrast enhanced Flat Detector CT
PROCEDURE
Lead Sponsor
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Collaborators
NCT07371455
NCT06258538
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT05093673