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Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS. | Clinical Trials | Clareo Health

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Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.

Analgesic Non Inferiority of the Thoracic Bi-block Combining an Erector Spinae Muscle Plane Block and a Serratus Anterior Muscle Plane Block in Comparison With Thoracic Epidural for Video-Assisted Thoracic Surgery.

NCT04538235•University Hospital, Montpellier

View on ClinicalTrials.gov

Summary

Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS. The aim of the study is to compare the analgesic efficacy of thoracic epidural with that a "Bi-block" combining an Erector Spinae muscle plane Block (ESP) and a Serratus Anterior Block (SAP) in patients undergoing VATS for lung or pleural surgery. Our main hypothesis is that the analgesic efficacy of the Bi-block, assessed by morphine consumption, is not inferior to that provided by a thoracic epidural during the first 48 hours after VATS. We conducted a age, gender and type of surgery-matched retrospective cohort study in the Department of Thoracic Anesthesia of the Montpellier University Hospital (France).

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•To be over 18.
•To be scheduled for VATS in the center of the study during the study period.
•Thoracic Epidural analgesia of Bi-block analgesia.

Exclusion Criteria

•Chronic pain or opioid use before surgery (6 months).
•Postoperative hospitalization in ICU during the first two days.
•Postoperative surgical complication needing surgical revision during the first two days.
•Preoperative dementia or other psychiatric disease incompatible with VAS pain scoring.

Locations (1)

Intensive Care Unit, D - University hospital of Montpellier

Montpellier, France

Key Dates

Start Date

October 20, 2019

Primary Completion Date

December 31, 2019

Completion Date

December 31, 2019

Last Updated

September 4, 2020

Enrollment

ACTUAL participants

Conditions

Erector Spinae Muscle Plane BlockSerratus Anterior Muscle Plane BlockVideo-Assisted Thoracic SurgeryLung CancerPleural DiseasesThoracic EpiduralAnalgesiaEnhanced Recovery After Surgery

Interventions

Thoracic Regional Analgesia

PROCEDURE

Optimal Level of PEEP in Protective One-lung Ventilation

NCT03856918

Video-assisted Thoracic SurgeryPostoperative Atelectasis+1 more

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UNKNOWN

Pulmonary Nodule Localization Prospective Validation

NCT04690790

Video-assisted Thoracic SurgeryPulmonary Nodules

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 4, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.

Inclusion Criteria

Exclusion Criteria

Optimal Level of PEEP in Protective One-lung Ventilation

Pulmonary Nodule Localization Prospective Validation

Echocardiographic Evaluation of the Change on Pulmonary Blood Flow and Cardiac Function During One-lung Ventilation