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Hemodynamic Changes Due to Prone Position in Healthy Volunteers
Perioperative prone position may be associated with hemodynamic instability. The causes of instability have not yet been precisely elucidated. The aim of this study is to demonstrate physiological changes during prone positioning in healthy volunteers .
The prone position could decrease the cardiac index (CI), mainly due to reduction in stroke volume, with little changes in heart rate. Mean arterial pressure (MAP) could be maintained by increased systemic vascular resistance (SVR) in the majority of patients. The aim of this study is to describe hemodynamic changes in two different surgical prone positions in 10 healthy non-anesthetized volunteers (flat position and using a support system allowing a free abdomen) by non-invasive measurement of hemodynamics (ClearSight, Edwards) and indirectly evaluated intra-abdominal pressure using ultrasound. The ClearSight system provides advanced hemodynamic parameters (cardiac index CI, stroke volume SV, stroke volume variation SVV, systemic vascular resistance SVR, mean arterial pressure MAP) from a finger cuff.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
University Hospital Hradec Kralove
Hradec Králové, Czechia
Start Date
June 8, 2020
Primary Completion Date
August 31, 2020
Completion Date
December 20, 2020
Last Updated
November 30, 2022
10
ACTUAL participants
prone position
PROCEDURE
Lead Sponsor
University Hospital Hradec Kralove
NCT05515484
NCT06740903
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