Thermoregulation Among Individuals With First-episode Psychosis

You may be eligible if

• Eligibility for Individuals with First-Episode Psychosis:
• 1. Diagnosis of a schizophrenia-spectrum disorder or mood disorder with psychotic features as determined using the Structured Clinical Interview for the DSM-5 .
• 2. Less than 5 years since the onset of frank psychotic symptoms as determined using the Symptom Onset in Schizophrenia Inventory.
• 3. No evidence of a pre-existing intellectual disability defined as a premorbid IQ \>70 as estimated using the Reading subtest of the Wide Range Achievement Test-4.
• Eligibility for Individuals without First-Episode Psychosis:
• 1. No diagnosis of a schizophrenia-spectrum disorder or mood disorder with psychotic features as determined using the Structured Clinical Interview for the DSM-5.
• 2. No evidence of a pre-existing intellectual disability defined as a premorbid IQ \>70 as estimated using the Reading subtest of the Wide Range Achievement Test-4.
• Eligibility for Individuals with and without First-Episode Psychosis:
• 1. Ages 18 - 35
• 2. No evidence of swallowing difficulties as assessed using the Swallowing Disturbance Questionnaire \[SDQ\]. defined as (i) a score \<5 on the SDQ oral phase questions, (ii) a score \<11.5 on the laryngopharygeal phase SDQ questions, and a total SDQ score \< 12.5.
• 3. Not meeting diagnostic criteria for a substance use disorder over the past month as determined using the Structured Clinical Interview for the DSM-5 .
• 4. No current or past diagnosis of a medical condition known to affect thermoregulatory Functioning as assessed using the Health Conditions that Affect Thermoregulation questionnaire
• 5. Per recommendations from the manufacturer of the CorTemp continuous temperature sensor, we will not enroll:
• 1. Individuals who weigh less than 80 pounds
• 2. Individuals diagnosed with known or suspected obstructive diseases of the gastrointestinal tract
• 3. Individuals with a history of gag reflex disorders or impairments
• 4. Individuals with previous or scheduled gastrointestinal surgery
• 5. Individuals having felinization of the esophagus
• 6. Individuals with conditions that would result in hypomotility of the GI tract.
• 7. Individuals scheduled to undergo Magnetic Resonance Imaging or Nuclear Magnetic Resonance in the next month
• 8. Individuals with cardiac pacemaker or other implanted electric medical devices