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AuRA Study: Association of Mood With Risk for Atherosclerosis
The investigators will aim to determine the association of mood disorders (MDO) with preclinical and clinical cardiovascular (CVD) risk factors among children. The investigators will also aim to identify traditional and non traditional predictors of CVD risk among children with MDO.
This research is being done to determine if mood disorders in children have an impact on stiffness of arteries and/or cause the arteries to not work as well and if MDOs impact blood pressure over a 24 hour period of time.The investigators also want to determine if children with mood disorders have any risk factors or blood tests that can predict how stiff arteries are or how well arteries function and if these are associated with cardiovascular disease risk. The investigators also want to determine if children with mood disorders have greater adverse childhood experiences, worse emotional regulation and poorer quality of sleep. The investigators hope that information from this study could help in earlier detection of cardiovascular disease risk in children.
Age
0 - 22 years
Sex
ALL
Healthy Volunteers
No
Johns Hopkins School of Medicine Division of Pediatric Nephrology
Baltimore, Maryland, United States
Start Date
March 11, 2020
Primary Completion Date
May 31, 2022
Completion Date
May 31, 2022
Last Updated
August 23, 2022
37
ACTUAL participants
Cardiovascular Assessments
DIAGNOSTIC_TEST
Actigraphy
DIAGNOSTIC_TEST
Laboratory assessments
DIAGNOSTIC_TEST
Emotional/ Behavioural assessments
BEHAVIORAL
Lead Sponsor
Johns Hopkins University
Collaborators
NCT02417740
NCT07073820
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT07480265