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Giving a Low Carbohydrate Diet to Overcome Hypertension | Clinical Trials | Clareo Health

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Giving a Low Carbohydrate Diet to Overcome Hypertension

A Pilot Study Comparing Dietary Approaches to Decrease Hypertension in a Lower Income, African American Population at Risk for Cardiovascular Disease

NCT04230928•Baylor Research Institute

View on ClinicalTrials.gov

Summary

This study will test the preliminary efficacy of adding a very low carbohydrate dietary intervention to the evidence-based DPP-GLB on blood pressure reductions for lower-income AA men and women in a community-based clinic.

Detailed Description

This study will evaluate the effects of consuming a very low carbohydrate (VLC) diet in a sustainable community care setting, in addition to routine medical care, to African American (AA) with pre-hypertension, hypertension (stage 1-3), or cardiovascular disease risk factors. This study will also secondarily assess the feasibility of following a VLC diet in a low-income, AA population.

Eligibility

Age

18 - 74 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1\) men and women aged ≥ 18 years
•2\) willingness to participate in a 10-month study
•3\) systolic blood pressure \> 120 mm/Hg +/- diastolic blood pressure \> 80 mm/Hg
•4\) African American race

Exclusion Criteria

•1\) diagnosed congestive heart failure
•2\) Hypertension stage 4 or higher (e.g., SBP \>180 mm/Hg; DBP \> 110 mm/Hg)
•3\) received or needing more than 3 anti-hypertensive medications
•4\) pregnant or planning to become pregnant
•5\) receiving or needing a heart transplant
•6\) Using injected long or short-acting insulin for diabetes treatment
•7\) not African American race
•8\) unable to speak and read English with fluency

Locations (1)

Baylor Research Institute

Dallas, Texas, United States

Key Dates

Start Date

March 5, 2020

Primary Completion Date

November 18, 2021

Completion Date

June 30, 2023

Last Updated

March 2, 2026

Enrollment

ACTUAL participants

Conditions

HypertensionAfrican AmericansDiet, Carbohydrate-RestrictedRisk Reduction Behavior

Interventions

Very low carbohydrate diet

OTHER

Standard DPP-GLB diet

OTHER

Standard DPP-GLB program modules

BEHAVIORAL

Natural History of Noncirrhotic Portal Hypertension

NCT02417740

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RECRUITING

Homocysteine and Early Diastolic Dysfunction in Newly Diagnosed Hypertension

NCT07480265

Hypertension (HTN)Hyperhomocysteinemia+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 2, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Giving a Low Carbohydrate Diet to Overcome Hypertension

Inclusion Criteria

Exclusion Criteria

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