Previous use of any Botulinum toxin in facial areas within 9 months prior to study treatment.

Anticipated need for treatment with botulinum toxin of any serotype for any reason during the study (other than the investigational product).

Female who is pregnant, breast feeding, or intends to conceive a child during the study.

Known allergy or hypersensitivity to any component of the investigational product (QM1114-DP) or any botulinum toxin serotype.

Long-term Treatment of Moderate to Severe Glabellar Lines and Lateral Canthal Lines