A Study to Evaluate AI-09 In Participants With Glabellar Lines

Exclusion Criteria

• •the inability to substantially lessen glabellar lines by physically spreading them apart
• •eyelid ptosis, and/ or excessive weakness or atrophy in the target muscle(s)
• •presence or history of "dry eye"
• •history of periocular surgery, brow lift or related procedures, or deep dermal scarring
• •concurrent or recent (within the last 6 months) use of any other botulinum toxin drug product anywhere in the body
• •history of immunization or hypersensitivity to any botulinum toxin serotype
• •history of non-response to any prior botulinum toxin treatments anticipated need for treatment with botulinum toxin of any serotype for any reason during the trial (other than the investigational treatment)
• •any medical condition that may put the subject at increased risk with exposure to botulinum toxin including diagnosed myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis, or any other condition that might interfere with neuromuscular function
• •pregnancy or lactation
• •application of any topical prescription medication to the treatment area within 14 days prior to treatment
• •participation in another investigational drug trial or receiving any investigational treatment(s) within 30 days of Baseline (Day 0)
• •alcohol or drug abuse within the past 3 years
• •refusal or inability with the subject's ability to give informed consent or comply with the requirements of the protocol for any reason