A Study to Investigate the Safety and Efficacy of YY003 in Adults with Moderate to Severe Glabellar Lines

Exclusion Criteria

• •1. Known allergy or hypersensitivity to any components of the investigational product or any botulinum toxin serotype.
• •2. A history or presence of ptosis, significant facial asymmetry, excessive dermatochalasis at screening or baseline.
• •3. A history or presence of facial nerve palsy at screening or baseline.
• •4. A positive HIV, hepatitis B or hepatitis C test at screening.
• •5. History or presence of other concomitant diseases which are assessed by the investigator to be unsuitable for participation in this clinical research.
• •6. History of drug or alcohol abuse.
• •7. History or presence of epilepsy.
• •8. Have a serious mental disorder that, in the Investigator's opinion, may affect participant compliance with the study.
• •9. Female who is pregnant or breast feeding.
• •10. Abnormal laboratory tests that, in the Investigator's assessment, are not appropriate for participation in this study.
• •11. Participation in an investigational device or drug study within 30 days or 5 half-lives (whichever is longer) prior to screening.
• •12. Study center personnel, close relatives of the study center personnel, employees or close relatives of employees at the sponsor company.