Erlotinib for Hepatocellular Carcinoma Chemoprevention

Inclusion Criteria

• •Adults (≥ 18 years-old)
• •Clinically and/or histologically diagnosed advanced liver fibrosis or cirrhosis
• •No active hepatic decompensation
• •No prior history of HCC
• •FIB-4 index \> 3.25
• •PLSec score ≥ 3
• •Adequate hematologic, hepatic, and renal function, Karnofsky performance status score ≥70
• •Both sexes and all racial/ethnic groups will be considered