A Study to Explore the Role of Gut Flora in ALS

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Amyotrophic Lateral Sclerosis

NCT04150809•ProgenaBiome

Summary

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding ALS

Detailed Description

The goal of this Research Study is to better understand how the genetic information in subject's microbiome correlates to the information provided in surveys and in medical records regarding ALS

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study
•2. Male or female patients of any age (interest is given to children to compare with mothers).
•3. Diagnosis of ALS

Exclusion Criteria

•1. Refusal to sign informed consent form
•2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy.
•3. Postoperative stoma, ostomy, or ileoanal pouch
•4. Participation in any experimental drug protocol within the past 12 weeks
•5. Treatment with total parenteral nutrition
•6. Any clinically significant evidence of disease that could interfere with the subject's ability to enter the trial
•7. Inability to adequately communicate with the investigator or their respective designee and/or comply with the requirements of the entire study

Locations (1)

ProgenaBiome

Ventura, California, United States

Key Dates

Start Date

March 2, 2020

Primary Completion Date

March 1, 2030

Completion Date

July 1, 2030

Last Updated

June 5, 2025

Conditions

ALSAmyotrophic Lateral SclerosisMotor Neuron Disease

Interventions

No intervention

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 5, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Study to Explore the Role of Gut Flora in ALS

Inclusion Criteria

Exclusion Criteria

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