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The purpose of this study is to see how an Intermittent Calorie Reduced Diet (IRCD) that mimics fasting (also known as a fasting mimicking diet, FMD) effects inflammation in patients with mild to moderate Crohn's disease (CD). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and CD are very limited. Diets that mimick fasting have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after five-day periods of the IRCD, and may provide rationale for its use to treat CD.
As above
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
Stanford University
Palo Alto, California, United States
Start Date
December 18, 2019
Primary Completion Date
March 12, 2024
Completion Date
May 6, 2024
Last Updated
April 17, 2025
86
ACTUAL participants
Intermittent Reduced Calorie Diet (IRCD)
OTHER
Lead Sponsor
Stanford University
NCT06226883
NCT07245394
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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