Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients

Exclusion Criteria

• •Severe disability after the event that qualified the patient for the study, defined as a modified Rankin (mRankin) scale equal to or greater than 4.
• •Being part of another clinical trial involving interventions for cardiovascular prevention.
• •Body mass index \> 45 kg/m2.
• •Pregnancy or Breastfeeding.
• •Secondary hypertension.
• •Class IV Canadian Cardiovascular Society (CCS) Resting Angina.
• •Acute coronary syndrome in the last six months
• •Severe renal dysfunction with GFR \< 20 mL/min/1.73m2 calculated by the CKD-EPI equation
• •Refusal to consent.
• •Symptomatic heart failure - Class IV New York Heart Association (NYHA) or ejection fraction \<35% on Doppler echocardiography.
• •Conditions that, at the investigators' discretion, limit the patient's participation in the study, including but not limited to the following:
• •* Recent history of alcohol and illicit drug abuse.
• •* Psychiatric comorbidities (severe depression, schizophrenia, psychosis, etc.).
• •* History of poor drug adherence and no attendance at consultations.
• •* Planning to change of address in the next four years.
• •* Planning to be absent from home city for more than three months in the next year.
• •* Residing in the same residence of another patient previously included in this study.