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Eleven men with myotonic dystrophy type 1 (DM1) underwent a 12-week lower-limb strength training program. The training program consisted of 3 series of 6 to 8 maximal repetitions of 5 different exercises: Leg extension, leg press, hip abduction, squat and plantar flexion. Training sessions were closely supervised and took place twice a week. It is hypothesised that the training program will induce muscular hypertrophy despite the genetic defect. The training program should also have positive effects on function. The participants were evaluated at baseline, week 6, week 12, month 6 and month 9 to see the effects of the training program and if these effects are maintained over time.
Age
30 - 65 years
Sex
MALE
Healthy Volunteers
No
Groupe de recherche interdisciplinaire sur les maladies neuromusculaires
Saguenay, Quebec, Canada
Start Date
July 1, 2017
Primary Completion Date
June 22, 2018
Completion Date
June 22, 2018
Last Updated
December 15, 2021
11
ACTUAL participants
Training program
OTHER
Lead Sponsor
Élise Duchesne
Collaborators
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07008469