Effect of Peri-operative Immunonutrition on Recurrence and Infections in Crohn's Disease Patients

Exclusion Criteria

• •Patients \< 18 years old;
• •Pregnant or breastfeeding women;
• •Diagnosis of undetermined colitis;
• •Concomitant diagnosis of malignancy;
• •Established malnutrition, according to clinical definition, requiring nutritional intervention;
• •Patients with more than two criteria for high risk of recurrence among the following: previous abdominal resection, penetrating disease phenotype or active smoking;
• •Any condition that, in the opinion of the investigator, can interfere with the consent procedure or the conduction of the trial;
• •Patients known to have allergic history to any component of the investigational product;
• •Patient with liver and kidney dysfunction (alanine aminotransferase ALT ≥ 2 times the upper limit of normal; total bilirubin TBIL ≥ 2 times the upper limit of normal; creatinine Cr ≥ 2 times the upper limit of normal);
• •Patients diagnosed with diabetes or fasting blood glucose≥ 10mmol/L;
• •Planned recovery shorter than 48 hours;
• •Surgery in emergency setting;
• •Any concomitant surgery not related to CD or perianal CD.