Lifestyle Interventions for the Treatment of Non-alcoholic Fatty Liver Disease in Overweight and Obese Adults

Exclusion Criteria

• •Patients with other diseases that can lead to fatty liver;
• •Patients use amiodaron, methotrexate, tamoxifen, glucocorticoid, estrogen, and the other medications that affect weight within 3 months;
• •Patients with serious liver dysfunction (AST or/and ALT \>3 times of the upper limit of normal), or renal dysfunction (serum creatinine \>the upper limit of normal);
• •Patients with diseases that need control of dietary protein intake;
• •Patients with diseases that affect food digestion and absorption;
• •Patients with diagnosed diabetes or those with significantly elevated blood glucose (fasting blood glucose ≥7.0 mmol/L and/or random blood glucose ≥11.1 mmol/L);
• •Patients with severe cardiovascular and cerebrovascular diseases or severe hypertension (Grade 3); anemia; mental illness or memory disorder; epilepsy or antiepileptic treatment;
• •Patients with secondary obesity;
• •Patients with cancer, active tuberculosis, AIDS and other infectious diseases;
• •Pregnancy or lactation;
• •Physical disability.