The Comparison of Uniportal and Tubeless Video Assisted Thoracic Surgery and Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Disease

Exclusion Criteria

• •1. Severe pulmonary dysfunction: forced vital capacity (FVC) ≤65% or carbon-monoxide diffusion coefficient (DLco) ≤45% of predicted value
• •2. Pulmonary hypertension: An estimated systolic pulmonary artery pressure\>50mmHg on echocardiography
• •3. Abnormal coagulation parameters or thrombocytopenia (\<50\*109/L)
• •4. Severe comorbidities leading to inoperable condition
• •5. Patients cannot give consent or refuse biopsy