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UNKNOWNNCT03939260

ECCO2R - Mechanical Power Study

Although mechanical ventilation remains the cornerstone of ARDS treatment, several experimental and clinical studies have undoubtedly demonstrated that it can contribute to high mortality through the ...

Lead sponsor: University of Milan•1 locations•View source on ClinicalTrials.gov

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Contacts

Davide Chiumello, Professor

CONTACT

+390281844020 chiumello@libero.it

Sponsors

Lead Sponsor

University of Milan

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•ARDS patients undergoing mechanical ventilation with:
•PaO2/FiO2 \<150 with a level of positive end expiratory pressure (PEEP) of 10 cmH2O or higher with a FiO2 \> 0.5
•Plateau pressure of 28 cmH2O or higher with tidal volume of 6 ml/Kg of ideal body weight
•Mechanical power of 18 J/min or higher.

Exclusion Criteria

•\<18 years of age
•Pregnancy
•Obesity with BMI\> 30
•Platelets \<30 G/l
•Decompensated heart failure or acute coronary syndrome
•Acute brain injury
•Contraindication for systemic anticoagulation (for example, gastrointestinal bleeding, recent cerebrovascular accident, or chronic bleeding disorder, recent major surgery)
•Patient moribund, decision to limit therapeutic interventions
•Catheter access to femoral vein or jugular vein impossible
•Pneumothorax.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 6, 2019Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment15

Start dateMar 2019

Last updatedMay 6, 2019

Condition

ARDS, Human Extracorporeal CO2 Removal Mechanical Power

Locations shown

ASST-Santi Paolo e Carlo, San Paolo Hospital

Milan

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 6, 2019Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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