Macular Involvement in Diabetic Retinopathy Evaluated With Swept-Source OCT

Exclusion Criteria

• •Substantial media opacities that would preclude successful imaging
• •* Active intraocular inflammation (grade trace or above) in either eye like infectious conjunctivitis, keratitis, scleritis, endophthalmitis as well as idiopathic or autoimmune-associated uveitis in either eye
• •* Structural damage to the center of macula in the study eye
• •* History of prior panretinal photocoagulation
• •* History of treatment with intravitreal agents over the prior 6 months
• •* Macular edema involving the central subfield
• •* Prior history of vitrectomy
• •* Atrophy of retinal pigment epithelium, subretinal fibrosis, laser scar within foveal avascular zone (FAZ) or organized hard exudate plaques
• •* Substantial non-diabetic intraocular pathology in the study eye including retinal vascular occlusion, retinal detachment, macular hole, choroidal neovascularization, macula dystrophies
• •* Intraocular surgery (including cataract surgery, YAG laser capsulotomy) in the study eye within 3 months preceding Day 0, or history of corneal transplantation in the study eye
• •* Uncontrolled glaucoma in the study eye (defined as intraocular pressure ≥ 25 mmHg despite treatment with anti-glaucoma medication)or history of glaucoma filtration surgery
• •* Inability to obtain fundus images of sufficient quality to be analyzed and graded