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Weight Loss and Cognitive Function in Middle-Aged and Older Adults
More than two-thirds of middle-aged and older adults are overweight, which places them at greater risk of disability and higher medical expenses. Lifestyle interventions which promote weight loss for this population are needed. However, it is not known how different weight loss approaches impact brain (cognitive) functions, such as memory and attention. The investigator's investigation aims to improve adherence to a hypocaloric diet prescription through improved attention and inhibitory control, reduced hunger, and increased satiety. The objectives of this pilot study are to: 1) determine the feasibility and establish proof-of-concept; 2) establish proficiency and feasibility of the proposed cognitive function assessments; and 3) obtain preliminary data for effect size generation.
Age
50 - 75 years
Sex
ALL
Healthy Volunteers
Yes
Virginia Tech
Blacksburg, Virginia, United States
Start Date
August 6, 2018
Primary Completion Date
August 14, 2019
Completion Date
March 31, 2020
Last Updated
March 21, 2025
33
ACTUAL participants
Hypocaloric diet with hunger reduction strategy
BEHAVIORAL
Hypocaloric diet without hunger reduction strategy
BEHAVIORAL
Lead Sponsor
Virginia Polytechnic Institute and State University
NCT06277232
NCT07395973
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT05301413