Study of the Fecal Microbiome in Patients With Parkinson's Disease

Exclusion Criteria

• •Unable to take multiple capsules orally.
• •Montreal Cognitive Assessment (MoCA) Score less than or equal to 23.
• •Atypical, vascular or drug-induced Parkinsonism.
• •Clinical features of psychosis or refractory hallucinations.
• •Unstable Parkinson's disease symptomatic therapy (defined as recent changes or additions to the PD regimen).
• •Compromised immune system (e.g. primary immune disorders or clinical immunosuppression due to a medical condition or medication e.g. taking systemic steroids greater than 20 milligrams (mg) a day or prednisone-equivalent)
• •Receipt of systemic non-topical antibiotic therapy currently or within 14 days of enrollment.
• •Prior Deep Brain Stimulation, or surgical intervention for PD, intravenous glutathione therapy or stem cell therapy.
• •History of medium or large vessel cerebrovascular accidents.
• •History of use of an investigational drug within 90 days prior to the screening visit.
• •Positive results for human immunodeficiency virus (HIV) or Hepatitis B / C.
• •Current history for active states of Inflammatory bowel disease, Irritable bowel syndrome, microscopic colitis, celiac disease, short gut syndrome, colostomy, colectomy, gastrointestinal fistulae or strictures.
• •History of significant uncontrolled systemic disease that in the opinion of the study investigator could interfere with study participation and/or objectives.
• •Life expectancy of less than 1 year.
• •In the opinion of investigator, subject for any reason, should be excluded from the study