Age

18–any

Sex

ALL

Healthy volunteers

Not accepted

NSCLC with preoperative pathological evidence,
Pure solid nodule or part-solid (\>50%) ground glass nodule on CT scan
Clinical stage tumor-1 to 3, clinical stage node-0, clinical stage metastasis-0, (except clinical stage tumor-3 for chest wall, pericardium or phrenic nerve invasion)
Video-assisted thoracoscopic lobectomy or bi-lobectomy

Pneumonectomy, segmentectomy, non anatomic resection
History of thoracic surgery on the same side
Necessity to perform a non-anatomic resection in addition to the lobectomy
No preoperative histological diagnosis
Pure ground glass nodule on CT scan
Clinical stage tumor-4 or 3 for chest wall, pericardium or phrenic nerve invasion
Clinical stage node ≥1
Neoadjuvant therapy
Second cancer or cancer in the past 5 years
First approach through thoracotomy with ribs spreading
Pregnancy, \<18 years of age
Pulmonary adherences/symphysis found during surgery (impossible to perform the first blood sample without lung manipulation)

Sequence of Vessel Interruption and Circulating Tumor Cells in Surgical Lung Cancer